Zylkene Calming Chews for Large Dogs Nutritional Supplement Chews 450mg offer a reliable, gentle way to help your dog cope with everyday stress and challenging situations. Many dogs experience anxiety triggered by changes in routine, loud noises, travel, vet visits, or separation from their owners. These moments can lead to behaviours such as pacing, whining, trembling, hiding or destructive habits. Zylkene Chews provide a safe and effective option to support calm behaviour without sedation, helping your dog feel more secure and relaxed.
Zylkene Calming Chews for Large Dogs contain alpha-casozepine, a natural milk-derived protein known for its calming properties. This ingredient works by supporting the natural relaxation pathways in the brain, making it easier for dogs to settle when faced with stressful triggers. Because the formula is non-drowsy, dogs remain alert, responsive and able to interact normally with their environment. This makes Zylkene suitable for both short-term and longer-term use, depending on your dog’s needs.
These 450mg Zylkene Calming Chews for Large Dogs are specifically formulated for large dogs weighing between 15kg and 60kg. The soft chew format is highly palatable, making them easy to give as a treat or mixed with food. Many dog owners appreciate how simple and stress-free the administration is, as anxious dogs may be reluctant to accept tablets or capsules. With Zylkene Chews, supporting your dog’s emotional wellbeing is straightforward and positive.
Zylkene is particularly useful during predictable stressful events. Before travel, grooming appointments, moving house, fireworks, thunderstorms or major household changes, giving Zylkene in advance can help reduce the intensity of your dog’s worry. For dogs experiencing ongoing anxiety, such as those adapting to a new home or struggling with mild separation issues, Zylkene can be given daily as part of a broader behaviour-support plan.
These chews can also assist dogs who become unsettled when exposed to new environments, visitors, other animals or unfamiliar settings. Whether you are introducing your dog to a new routine or helping them cope with a temporary challenge, Zylkene is designed to support balanced, calm behaviour in a safe and gentle way.
Zylkene is produced by Vetoquinol, a trusted global veterinary company known for high-quality supplements and animal health products. The formula does not contain preservatives or artificial flavours, and it is not a sedative or tranquilliser. It works naturally with your dog’s body to promote relaxation.
If you are searching for a calming supplement that is easy to give, non-sedating and backed by scientific research, Zylkene Calming Nutritional Supplement Chews 450mg for large dogs offer an excellent solution. These chews help dogs face stressful moments with greater ease, supporting their emotional wellbeing and giving owners peace of mind.
FEATURES
• Suitable for large dogs 15–60kg
• Contains natural milk-derived alpha-casozepine
• Non-drowsy, non-sedating calming support
• Helps during travel, vet visits, loud noises, visitors and routine changes
• Soft, easy-to-chew, highly palatable
• Can be used short-term or daily long-term
• Made by Vetoquinol
DIRECTIONS FOR USE
Administer the recommended daily amount based on your dog’s weight. Give directly as a chew or mix with food. For predictable stressful events, begin use 1–2 days in advance. Always follow advice from your veterinarian if using long-term.
INGREDIENTS
Alpha-casozepine (milk protein hydrolysate), natural flavourings, soft chew base.





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